Design and synthesis of organic compounds via either FTE or Fee for Service
Custom synthesis and rapid scale-up (mg to kg)
Library design and synthesis
Synthetic route scouting
An efficient strategy for the discovery of kinase inhibitors by combination of diversity-oriented synthesis and selective screening is developed. Med. Chem. Commun., 2016, 7, 1946. Patent: 201110066820.7
A novel tricyclic thiazepine compound as a tubulin polymerization inhibitor against H460TaxR，IC50 = 350 nM. Cell Death and Disease, 2016, 7, e2143；Patent: WO 2012/163236 A1.
Some early projects by CDS scientists
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